Flexizymes that enable to reprogram the genetic code

Is A Source Of Genetic Variation That Refers To A Random Error In The Genetic Code

The chart below shows the codons that make up the genetic code and the sequence of A. The introduced gene will cause more diversity in the potato's genome, thus Sometimes an error is made during this separation and homologous be genetically engineered to recognize and destroy random cells in the body. is a source of genetic variation that refers to a random error in the genetic code. Delete. Ca...

To Code or Not to Code, That Is the Question

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation

Imbalances in endoplasmic reticulum (ER) proteostasis are associated with etiologically-diverse degenerative diseases linked to excessive extracellular protein misfolding and aggregation. Reprogramming of the ER proteostasis environment through genetic activation of the Unfolded Protein Response (UPR)-associated transcription factor ATF6 attenuates secretion and extracellular aggregation of amy...

Genetic Mutations that Cause Coronary Artery Disease

Expanding the genetic code.

Although chemists can synthesize virtually any small organic molecule, our ability to rationally manipulate the structures of proteins is quite limited, despite their involvement in virtually every life process. For most proteins, modifications are largely restricted to substitutions among the common 20 amino acids. Herein we describe recent advances that make it possible to add new building bl...